ADME-Tox & DMPK

Comprehensive Preclinical ADME-Tox Support: From Human Gut Models to Off-Target Studies

ADME-Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicology) is a critical component of drug development, ensuring the safety and efficacy of new compounds. We offer comprehensive support in preclinical ADME-Tox, utilizing advanced human gut models and conducting off-target studies. As a Contract Research Organization (CRO) and solution provider, we partner with customers to optimize their drug development process, delivering reliable and actionable insights.

Human Gut Models

Our RepliGut™ human gut models provide drug absorption and metabolism insights and allows inflammation and IBD studies.

Off-Target Toxicity

Explore our normal Tissue Microarrays for your large molecule development

 

Animal Cells

Request a custom isolation of intestinal, liver or kidney cells from cat, dog, pig, mouse and rat

Metabolic Assay

From drug metabolism to cell cycle, our assays have you covered in every experiment

For Biology & Pharmaceuticals

Sellomics as a
Solution Partner

No drug is born equal, and every project is different. Our team have supported dozens of projects and takes pride in supporting each researcher in their work as they would expect from a colleague.

  • Step 1

    We sign an NDA and make sure we have clarity on goals, budget and timelines. You want to get results soon, we are here to make this happen.

  • Step 2

    With a pilot study you can collect the first results and flexibly evaluate the next steps. Our team will support you in drafting the study and finding the most flexible and cost effective solution.

  • Step 3

    Once the first results are in, you’ll need a reliable partner. Sellomics will help you scale your research and offer a partnership approach to long-term studies that ensures you meet milestones in time and on budget.

The Complete Package

Products for this Research Area

Normal TMA

Tissue Microarrays for Off-target research
Up to 200 spots
Screening services
Custom or ready-to-use
As block or slice

RepliGut ® Systems

Reproducible and scalable human intestine platform for ADME-Tox
2x Small Intestine Regions
3x Colon Regions
12 or 96-well formats
Stem cells from intestinal crypts
GI-Toxicity
Inflammation Studies
Intestinal Barrier Function
Intestinal Drug Disposition

Metabolic & Enzymatic Assays

High quality for metabolic screenings
>200 assays
3 quality controls
96-well format

Exclusive Products from these Partners