Drug Discovery Services

Introduction to Preclinical Drug Discovery

The journey of drug discovery is a complex and multi-faceted process, starting from the identification of potential drug targets to the development of lead compounds ready for clinical trials. Our comprehensive suite of products and services supports every stage of preclinical drug discovery, ensuring efficiency, accuracy, and innovation.

Target Identification and Validation

In the initial phase of drug discovery, identifying and validating therapeutic targets is crucial. Our extensive FFPE biobank provides high-quality, well-characterized samples essential for early discovery phases. We enhance target validation through our RNA in situ hybridization and antibody screening services, ensuring precise and reliable results. Additionally, our comprehensive range of ELISAs, antibodies, growth factors, and cytokines supports detailed molecular analyses, aiding in the robust validation of your drug targets.

Hit Identification and Lead Optimization

Once targets are validated, the next step involves identifying potential hits and optimizing lead compounds. Our high throughput screening services are designed to enhance the efficiency and accuracy of your research. Utilizing state-of-the-art liquid handling automation devices, we ensure precise and rapid processing of large sample volumes. Our extensive range of assay kits provides reliable and robust tools for various screening applications. Furthermore, our custom fermenters and bioreactors streamline the production of compounds, saving time and costs by fitting your specific process requirements.

Conclusion

Partner with us to leverage our advanced tools and comprehensive solutions, driving innovation and precision in your drug discovery processes. From target identification and validation to ADME-Tox studies and beyond, our products and services are designed to support and accelerate your research at every stage.

 

ADME-Tox Studies

ADME-Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicology) studies are critical for understanding the safety and efficacy of new compounds. We offer comprehensive support in preclinical ADME-Tox, utilizing advanced human gut models and conducting off-target studies. These models mimic human intestinal physiology, providing precise insights into drug absorption and metabolism. Our robust human biosample sourcing capabilities ensure access to high-quality, well-characterized specimens essential for reliable ADME-Tox evaluations.

Immunology and Inflammation Research

Understanding the immune response is vital in drug discovery, especially for therapies targeting autoimmune diseases and inflammatory conditions. Our human gut models for inflammatory bowel diseases (IBD) provide valuable insights into gut inflammation and immune responses. We offer a broad range of ELISAs, antibodies, growth factors, and cytokines for precise and reliable analysis of immune functions. Utilizing our state-of-the-art liquid handling devices, we enhance the efficiency and accuracy of your immunology research workflows.

Metabolic Research

Our metabolic research services support your investigation into metabolic processes and disorders with cutting-edge tools and resources. We offer a comprehensive range of metabolic and enzymatic assays, providing reliable and precise measurements for your studies. Our advanced human gut models simulate intestinal metabolism, offering valuable insights into nutrient absorption and metabolic interactions. Additionally, our robust human biosample sourcing capabilities ensure access to high-quality, well-characterized specimens, vital for accurate metabolic research.

Stem Cell Research

Our stem cell research services are designed to propel your studies with advanced tools and resources. We provide a wide range of growth factors and cytokines that are crucial for stem cell maintenance, differentiation, and proliferation. Our state-of-the-art liquid handling automation devices streamline your workflows, enhancing efficiency and precision. Our extensive selection of ELISAs and antibodies allows for accurate and reliable analyses of stem cell markers and related pathways, driving innovative discoveries in stem cell research.

For Biology & Pharmaceuticals

Sellomics as a
Solution Partner

No drug is born equal, and every project is different. Our team have supported dozens of projects and takes pride in supporting each researcher in their work as they would expect from a colleague.

  • Step 1

    We sign an NDA and make sure we have clarity on goals, budget and timelines. You want to get results soon, we are here to make this happen.

  • Step 2

    With a pilot study you can collect the first results and flexibly evaluate the next steps. Our team will support you in drafting the study and finding the most flexible and cost effective solution.

  • Step 3

    Once the first results are in, you’ll need a reliable partner. Sellomics will help you scale your research and offer a partnership approach to long-term studies that ensures you meet milestones in time and on budget.

The Complete Package

Products for this Research Area

FFPE Biobank

>1.000.000 samples
>30 years of biobanking
Rare samples
Blocks or slides

ELISAs, Antibodies, Growth Factors & Cytokines

>30.000 ELISAs
>30.000 Antibodies
>200 Growth Factors & Cytokines
Western Blot
IHC & IF
Immunoprecipitation
Flow Cytometry

Human Biospecimens

Fresh tissue
Cryopreserved tissue
Matched tissue
PBMCs
Liquid samples
Biofluids

Exclusive Products from these Partners